Category Archives: Uncategorized

We are grateful to the The American Cancer Society (ACS) as well as Yosemite, an oncology-focused venture capital firm, for their generous support of our work on epigenetic reprogramming of adoptive cell therapies to bolster memory formation. The ACS-Yosemite awards support innovative work in immuno-oncology as well as the use of Artificial Intelligence (AI) in cancer prevention, detection, treatment, and healthcare delivery.

Keely Ji was the latest graduate student in the lab to successfully complete her preliminary qualifying exams which involves a written thesis proposal and oral presentation to three HMS Immunology faculty member. Congratulations Keely!

The Sen lab team Sen-sationals participated in the MGH Cancer Center-sponsored Lab Olympics, with our lab T-shirt design winning second place! Huge props to Keely for the design and the whole lab for decorating the shirts!

We’re so excited that Snehanshu Chowdhury is coming to the lab as a joint postdoc between our group and our close collaborator Andy Elia’s group . Coming from India, Snehanshu did his PhD in Dr. Shilpak Chatterjee’s lab, where he focused on rewiring the metabolic programming of T cells in tumors. Apart from science, Snehanshu loves to read detective novels, cook and explore new places. Welcome Snehanshu!

Our latest work on the influence of the aged tumor microenvironment on T cell dysfunction is now out in Nature Immunology, led by Alex Chen in the lab and supported by lab members Sneha Jaiswal, Daniela Martinez, Cansu Yerinde, Keely Ji, Velita Miranda and others! Check out the full story at Nature Immunology, as well as the associated News and Views article and a lovely Research Highlight from ACIR.

Keely has been awarded the National Science Foundation’s fellowship for graduate students based on her proposed doctoral work. This prestigious grant includes multi-year funding support and access to professional development resources, recognizing the strength of her proposed work and future career in science. Congrats to Keely Ji!


We’re thrilled that Ranjan Maskey has joined the Sen Lab as lab manager, working hand in hand with Paola Lirofonis to keep things running smoothly. Welcome Ranjan!

The Sen Lab along with the Jan, Manguso, and Maus Labs were awarded one of the inaugural Breakthrough grants within the Krantz Center for Cancer Research for our collaborative efforts to re-engineer CAR-T cells for immunotherapy. We are so grateful to Jason and Keely Krantz for the generous support of our work!

The Sen Lab took a break from the lab benches for some team bonding with an Escape Room outing. It wasn’t easy, but we worked together to get out in time!

Daniela Martinez, the lab’s first graduate student, successfully completed her preliminary qualifying exams which involves a written thesis proposal and oral presentation to three HMS Immunology faculty member. Congratulations Daniela!

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